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PTOV1

Synonyms
ACID2, PTOV-1
External resources
Summary
This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
11,104
Likely benign
5,704
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on PTOV1 gene.

Phenotype class
Patients in 3billion (%)

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