Home > Gene Browser > PPP1R1C

PPP1R1C

Synonyms
IPP5
External resources
Summary
Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,780
Likely benign
1,406
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on PPP1R1C gene.

Phenotype class
Patients in 3billion (%)

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