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PPP1R15A

Synonyms
GADD34
External resources
Summary
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,377
Likely benign
2,498
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on PPP1R15A gene.

Phenotype class
Patients in 3billion (%)

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