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PLPPR3

Synonyms
LPPR3, LPR3, PRG-2, PRG2
External resources
Summary
The proteins in the lipid phosphate phosphatase (LPP) family, including PRG2, are integral membrane proteins that modulate bioactive lipid phosphates including phosphatidate, lysophosphatidate, and sphingosine-1-phosphate in the context of cell migration, neurite retraction, and mitogenesis (Brauer et al., 2003 [PubMed 12730698]).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
9,782
Likely benign
2,216
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on PLPPR3 gene.

Phenotype class
Patients in 3billion (%)

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