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PADI4

Synonyms
PAD, PAD4, PADI5, PDI4, PDI5
External resources
Summary
This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
5,477
Likely benign
20,263
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on PADI4 gene.

Phenotype class
Patients in 3billion (%)

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