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NKX3-1

Synonyms
BAPX2, NKX3, NKX3.1, NKX3A
External resources
Summary
This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,119
Likely benign
35
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on NKX3-1 gene.

Phenotype class
Patients in 3billion (%)

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