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NGFR

Synonyms
CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR
External resources
Summary
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
6,790
Likely benign
2,205
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on NGFR gene.

Phenotype class
Patients in 3billion (%)

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