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NDRG2

Synonyms
SYLD
External resources
Summary
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Alternative splicing results in multiple transcript variants.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
6,292
Likely benign
4,113
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on NDRG2 gene.

Phenotype class
Patients in 3billion (%)

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