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MIIP

Synonyms
IIP45
External resources
Summary
This gene encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. This protein also interacts with the cell division protein 20 and may be involved in regulating mitotic progression. This protein may function as a tumor suppressor by inhibiting the growth or certain cancers.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,968
Likely benign
11,426
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on MIIP gene.

Phenotype class
Patients in 3billion (%)

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