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MICAL2

Synonyms
Ebitein1, MICAL-2, MICAL2PV1, MICAL2PV2, MICALCL, mical-cL
External resources
Summary
The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
8,037
Likely benign
1,642
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on MICAL2 gene.

Phenotype class
Patients in 3billion (%)

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