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LSM8

Synonyms
NAA38
External resources
Summary
This gene encodes a member of the like-Sm family of proteins. The encoded protein consists of a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. This protein partners with six paralogs to form a heteroheptameric ring which transiently binds U6 small nuclear RNAs and is involved in the general maturation of RNA in the nucleus.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
767
Likely benign
375
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on LSM8 gene.

Phenotype class
Patients in 3billion (%)

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