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LSM3

Synonyms
SMX4, USS2, YLR438C
External resources
Summary
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.

Variant Counts

Variant classification counts, according to ACMG guideline on all identified variants among our tested samples, are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc.) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
7,319
Likely benign
3,210
Benign
0

Patient Phenotypes

No patients carry pathogenic or likely pathogenic variants on LSM3 gene.

Phenotype class
Patients in 3billion (%)

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