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LSM2

Synonyms
C6orf28, G7B, YBL026W, snRNP
External resources
Summary
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
9,780
Likely benign
270
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on LSM2 gene.

Phenotype class
Patients in 3billion (%)

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