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INSM1

Synonyms
IA-1, IA1
External resources
Summary
Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
862
Likely benign
147
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on INSM1 gene.

Phenotype class
Patients in 3billion (%)

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