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IER3

Synonyms
DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1
External resources
Summary
This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,236
Likely benign
30
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on IER3 gene.

Phenotype class
Patients in 3billion (%)

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