Home > Gene Browser > HSF1

HSF1

Synonyms
HSTF1
External resources
Summary
The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
37,964
Likely benign
33,244
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on HSF1 gene.

Phenotype class
Patients in 3billion (%)

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