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GNG3

Synonyms
HG3D
External resources
Summary
Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The gamma subunit determines the specificity of which signaling pathways will be affected by this particular complex. The protein encoded by this gene represents the gamma subunit of both inhibitory and stimulatory complexes.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,133
Likely benign
53
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on GNG3 gene.

Phenotype class
Patients in 3billion (%)

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