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GNG2

Synonyms
HG3F1
External resources
Summary
This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,762
Likely benign
955
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on GNG2 gene.

Phenotype class
Patients in 3billion (%)

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