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FRS3

Synonyms
FRS2-beta, FRS2B, FRS2beta, SNT-2, SNT2
External resources
Summary
This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
9,246
Likely benign
1,335
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on FRS3 gene.

Phenotype class
Patients in 3billion (%)

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