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FOXO1

Synonyms
FKH1, FKHR, FOXO1A
External resources
Summary
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Variant counts

Variant classification counts according to ACMG guideline on all identified variants among our tested samples are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
438
Likely benign
1,056
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on FOXO1 gene.

Phenotype class
Patients in 3billion (%)

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