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FFAR1

Synonyms
FFA1R, GPCR40, GPR40
External resources
Summary
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,052
Likely benign
803
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on FFAR1 gene.

Phenotype class
Patients in 3billion (%)

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