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FER

Synonyms
PPP1R74, TYK3, p94-Fer
External resources
Summary
The protein encoded by this gene is a member of the FPS/FES family of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome X.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
4,933
Likely benign
11,199
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on FER gene.

Phenotype class
Patients in 3billion (%)

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