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FDX1

Synonyms
ADX, FDX, LOH11CR1D
External resources
Summary
This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
4,470
Likely benign
646
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on FDX1 gene.

Phenotype class
Patients in 3billion (%)

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