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EIF3M

Synonyms
B5, GA17, PCID1, TANGO7, hfl-B5
External resources
Summary
This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,148
Likely benign
365
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on EIF3M gene.

Phenotype class
Patients in 3billion (%)

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