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EIF3J

Synonyms
EIF3S1, eIF3-alpha, eIF3-p35
External resources
Summary
This gene encodes a core subunit of the eukaryotic initiation factor 3 complex, which participates in the initiation of translation by aiding in the recruitment of protein and mRNA components to the 40S ribosome. There are pseudogenes for this gene on chromosomes 1, 3, and 9. Alternative splicing results in multiple transcript variants encoding different isoforms.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
7,870
Likely benign
639
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on EIF3J gene.

Phenotype class
Patients in 3billion (%)

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