Home > Gene Browser > DCAF12L1

DCAF12L1

Synonyms
KIAA1892L, WDR40B
External resources
Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
330
Likely benign
48
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on DCAF12L1 gene.

Phenotype class
Patients in 3billion (%)

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