Home > Gene Browser > DBF4B

DBF4B

Synonyms
ASKL1, CHIFB, DRF1, ZDBF1B
External resources
Summary
This gene encodes a regulator of the cell division cycle 7 homolog (S. cerevisiae) protein, a serine-threonine kinase which links cell cycle regulation to genome duplication. This protein localizes to the nucleus and, in complex with the cell division cycle 7 homolog (S. cerevisiae) protein, may facilitate M phase progression. Alternative splicing results in multiple transcript variants.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
3,136
Likely benign
1,087
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on DBF4B gene.

Phenotype class
Patients in 3billion (%)

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