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CMTM5

Synonyms
CKLFSF5
External resources
Summary
This gene encodes a member of the chemokine-like factor superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. The encoded protein may exhibit tumor suppressor activity. Alternative splicing results in multiple transcript variants.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
3,977
Likely benign
285
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CMTM5 gene.

Phenotype class
Patients in 3billion (%)

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