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CMTM1

Synonyms
CKLFH, CKLFH1, CKLFSF1
External resources
Summary
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,986
Likely benign
819
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on CMTM1 gene.

Phenotype class
Patients in 3billion (%)

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