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CADM3

Synonyms
BIgR, IGSF4B, NECL1, Necl-1, TSLL1, synCAM3
External resources
Summary
The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene.

Variant Counts

Variant classification counts, according to ACMG guideline on all identified variants among our tested samples, are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc.) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
3,045
Likely benign
419
Benign
0

Patient Phenotypes

No patients carry pathogenic or likely pathogenic variants on CADM3 gene.

Phenotype class
Patients in 3billion (%)

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