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APBA3

Synonyms
MGC:15815, X11L2, mint3
External resources
Summary
The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
6,373
Likely benign
3,014
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on APBA3 gene.

Phenotype class
Patients in 3billion (%)

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