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ZSCAN4

Synonyms
ZNF494
External resources
Summary
The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,092
Likely benign
212
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on ZSCAN4 gene.

Phenotype class
Patients in 3billion (%)

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