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XCL1

Synonyms
ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1
External resources
Summary
This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
22,581
Likely benign
21,815
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on XCL1 gene.

Phenotype class
Patients in 3billion (%)

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