Home > Gene Browser > VEZF1

VEZF1

Synonyms
DB1, ZNF161
External resources
Summary
Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. ZNF161 is a C2H2-type zinc finger protein (Koyano-Nakagawa et al., 1994

Variant counts

Variant classification counts according to ACMG guideline on all identified variants among our tested samples are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
1
Likely pathogenic
77
VUS
783
Likely benign
62
Benign
0

Patient phenotypes

Proportions of phenotypes among 78 patients carring pathogenic or likely pathogenic variants on VEZF1 gene are displayed below.

Phenotype class
Patients in 3billion (%)
Abnormality of the nervous system
64.1%
Abnormality of the musculoskeletal system
43.6%
Abnormality of the eye
38.5%
Abnormality of head or neck
30.8%
Abnormality of limbs
15.4%
Abnormality of the integument
12.8%
Abnormality of the ear
11.5%
Abnormality of the genitourinary system
11.5%
Growth abnormality
10.3%
Abnormality of the respiratory system
6.4%
Abnormality of the digestive system
5.1%
Abnormality of the cardiovascular system
3.8%
Abnormality of the immune system
3.8%
Abnormality of blood and blood-forming tissues
2.6%
Neoplasm
2.6%
Abnormality of prenatal development or birth
1.3%
Abnormality of the endocrine system
1.3%
Constitutional symptom
1.3%
Abnormal cellular phenotype
0%
Abnormality of metabolism homeostasis
0%
Abnormality of the breast
0%
Abnormality of the thoracic cavity
0%
Abnormality of the voice
0%

Have a question or need assistance? Ask here.

Send us your questions or comments related to the variant counts and/or patient phenotypes