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TOB1

Synonyms
APRO5, APRO6, PIG49, TOB, TROB, TROB1
External resources
Summary
This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
3,843
Likely benign
41
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on TOB1 gene.

Phenotype class
Patients in 3billion (%)

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