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RND2

Synonyms
ARHN, RHO7, RhoN
External resources
Summary
This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,063
Likely benign
152
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on RND2 gene.

Phenotype class
Patients in 3billion (%)

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