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RHPN2

Synonyms
P76RBE, RHOBP
External resources
Summary
This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
86,656
Likely benign
16,375
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on RHPN2 gene.

Phenotype class
Patients in 3billion (%)

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