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PRL

Synonyms
GHA1
External resources
Summary
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,258
Likely benign
306
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on PRL gene.

Phenotype class
Patients in 3billion (%)

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