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NUDT6

Synonyms
ASFGF2, FGF-AS, FGF2AS, GFG-1, GFG1
External resources
Summary
This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,996
Likely benign
183
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on NUDT6 gene.

Phenotype class
Patients in 3billion (%)

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