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NUDT3

Synonyms
DIPP, DIPP-1, DIPP1
External resources
Summary
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998

Variant counts

Variant classification counts according to ACMG guideline on all identified variants among our tested samples are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,475
Likely benign
292
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on NUDT3 gene.

Phenotype class
Patients in 3billion (%)

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