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NRM

Synonyms
NRM29
External resources
Summary
The protein encoded by this gene contains transmembrane domains and resides within the inner nuclear membrane, where it is tightly associated with the nucleus. This protein shares homology with isoprenylcysteine carboxymethyltransferase enzymes. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
5,278
Likely benign
1,113
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on NRM gene.

Phenotype class
Patients in 3billion (%)

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