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NPBWR2

Synonyms
GPR8
External resources
Summary
The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
8,325
Likely benign
1,036
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on NPBWR2 gene.

Phenotype class
Patients in 3billion (%)

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