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LRRC37A2

Synonyms
LRRC37
External resources

Variant counts

Variant classification counts according to ACMG guideline on all identified variants among our tested samples are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
114
Likely pathogenic
0
VUS
10,050
Likely benign
1,677
Benign
0

Patient phenotypes

Proportions of phenotypes among 113 patients carring pathogenic or likely pathogenic variants on LRRC37A2 gene are displayed below.

Phenotype class
Patients in 3billion (%)
Abnormality of the nervous system
32.7%
Abnormality of the cardiovascular system
27.4%
Abnormality of the musculoskeletal system
18.6%
Abnormality of head or neck
10.6%
Abnormality of the eye
10.6%
Abnormality of the genitourinary system
10.6%
Abnormality of the ear
9.7%
Growth abnormality
8%
Abnormality of the immune system
7.1%
Abnormality of the digestive system
6.2%
Abnormality of blood and blood-forming tissues
5.3%
Abnormality of the endocrine system
5.3%
Abnormality of limbs
4.4%
Abnormality of prenatal development or birth
4.4%
Abnormality of the integument
3.5%
Neoplasm
2.7%
Constitutional symptom
1.8%
Abnormality of the breast
0.9%
Abnormality of the voice
0.9%
Abnormal cellular phenotype
0%
Abnormality of metabolism homeostasis
0%
Abnormality of the respiratory system
0%
Abnormality of the thoracic cavity
0%

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