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LCN12

Synonyms
-
External resources
Summary
Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
18,652
Likely benign
6,579
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on LCN12 gene.

Phenotype class
Patients in 3billion (%)

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