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IRX3

Synonyms
IRX-1, IRXB1
External resources
Summary
IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,201
Likely benign
584
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on IRX3 gene.

Phenotype class
Patients in 3billion (%)

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