Home > Gene Browser > IGSF10

IGSF10

Synonyms
CMF608
External resources

Variant counts

Variant classification counts according to ACMG guideline on all identified variants among our tested samples are listed. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
174
Likely pathogenic
185
VUS
5,175
Likely benign
1,912
Benign
0

Patient phenotypes

Proportions of phenotypes among 349 patients carring pathogenic or likely pathogenic variants on IGSF10 gene are displayed below.

Phenotype class
Patients in 3billion (%)
Abnormality of the nervous system
36.7%
Abnormality of the musculoskeletal system
23.2%
Abnormality of the eye
19.8%
Abnormality of head or neck
18.1%
Abnormality of the cardiovascular system
17.2%
Growth abnormality
14.9%
Abnormality of the ear
13.5%
Abnormality of the genitourinary system
8.3%
Abnormality of the integument
8%
Abnormality of limbs
5.7%
Abnormality of the digestive system
4.9%
Abnormality of the immune system
4.6%
Abnormality of blood and blood-forming tissues
3.4%
Abnormality of the respiratory system
3.4%
Abnormality of the endocrine system
2.6%
Abnormality of prenatal development or birth
2%
Neoplasm
2%
Abnormality of the breast
1.1%
Constitutional symptom
1.1%
Abnormal cellular phenotype
0.3%
Abnormality of the voice
0.3%
Abnormality of metabolism homeostasis
0%
Abnormality of the thoracic cavity
0%

Have a question or need assistance? Ask here.

Send us your questions or comments related to the variant counts and/or patient phenotypes