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HOOK2

Synonyms
HK2
External resources
Summary
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,039
Likely benign
2,364
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on HOOK2 gene.

Phenotype class
Patients in 3billion (%)

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