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GNAT3

Synonyms
GDCA, HG1E
External resources
Summary
Sweet, bitter, and umami tastes are transmitted from taste receptors by a specific guanine nucleotide binding protein. The protein encoded by this gene is the alpha subunit of this heterotrimeric G protein, which is found not only in the oral epithelium but also in gut tissues. Variations in this gene have been linked to metabolic syndrome.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
1,485
Likely benign
468
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on GNAT3 gene.

Phenotype class
Patients in 3billion (%)

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