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GABRG1

Synonyms
-
External resources
Summary
The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
2,563
Likely benign
751
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on GABRG1 gene.

Phenotype class
Patients in 3billion (%)

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