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FRAT2

Synonyms
FRAT-2
External resources
Summary
The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.

Variant counts

The variants found in rare patients tested by 3billion are classified and counted according to ACMG guidelines. The variants with over 5% variant frequency in population genome databases ( gnomAD, dbSNP, etc) are excluded.

Pathogenic
0
Likely pathogenic
0
VUS
970
Likely benign
206
Benign
0

Patient phenotypes

No patients carry pathogenic or likely pathogenic variants on FRAT2 gene.

Phenotype class
Patients in 3billion (%)

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